Parotid Lesion

A parotid lesion is an abnormal growth or structural change involving the parotid gland, the largest of the salivary glands. The parotid glands are located in front of and below each ear and play an important role in saliva production. Parotid lesions are commonly discovered as a painless lump near the jaw or in front of the ear and may be benign or malignant. Because the facial nerve travels through the parotid gland, even relatively small lesions are evaluated carefully to determine their relationship to nearby structures.

Head Neck

What is it?

The parotid glands are located on both sides of the face in front of and below the ears. They release saliva into the mouth through the parotid duct, which opens near the upper teeth.

The facial nerve passes directly through the parotid gland and divides it into superficial and deep portions. Multiple lymph nodes are also located within the gland, which means both salivary gland tumors and lymph node–related conditions may appear as parotid masses.

Parotid lesions have many possible causes.

Benign tumors are the most common and include pleomorphic adenoma, the most frequent benign salivary gland tumor overall, and Warthin tumor, which occurs more commonly in older adults and smokers.

Other benign causes include cysts, enlarged intraparotid lymph nodes, inflammatory conditions such as sialadenitis, autoimmune disorders such as Sjögren syndrome, and salivary duct stones (sialolithiasis).

Malignant parotid tumors are less common but may include mucoepidermoid carcinoma, adenoid cystic carcinoma, acinic cell carcinoma, lymphoma, or metastatic disease spreading from nearby skin cancers involving the scalp, ear, or face.

Ultrasound is often the first imaging test used to evaluate a parotid lesion because it provides detailed information about lesion size, shape, vascularity, and internal structure without radiation exposure.

MRI of the head and neck with contrast is the preferred imaging test when more detailed evaluation is needed because it provides excellent soft tissue contrast and helps assess whether a lesion has benign or aggressive imaging features. MRI also evaluates the relationship between the lesion and nearby structures such as the facial nerve, muscles, lymph nodes, and deep neck spaces.

CT imaging may be used in select situations, particularly when evaluating salivary stones, calcifications, infection, trauma, or bone involvement.

Fine-needle aspiration biopsy is commonly performed when tissue diagnosis is needed before treatment planning.

Important to Know

Treatment depends on the type of parotid lesion. Inflammatory and infectious conditions are usually treated with medications, hydration, massage, or supportive care.

Salivary stones may sometimes be managed with minimally invasive procedures or surgery when symptoms persist.

Benign tumors are often surgically removed because they can continue to enlarge and, in some cases, may undergo malignant transformation over time.

When imaging or biopsy suggests malignancy, treatment is coordinated through a multidisciplinary head and neck oncology team and may involve surgery, radiation therapy, and occasionally chemotherapy.

Because preservation of facial nerve function is critically important, detailed imaging and surgical planning are central parts of treatment.

Follow-up imaging may be recommended to monitor lesion stability, recurrence, or treatment response.

Red flag symptoms include facial weakness or paralysis, rapid growth, persistent pain, numbness, hard or fixed texture, overlying skin changes, or enlarged neck lymph nodes. These symptoms require prompt medical evaluation.