Pancreatic Calcifications
Pancreatic calcifications are deposits of calcium within the pancreas that are visible on imaging. They most commonly occur as a result of chronic inflammation—especially chronic pancreatitis—but can also be seen with certain metabolic conditions, prior injury, or rarely in association with pancreatic tumors. Calcifications can vary in number and size and may indicate long-standing pancreatic disease.
What is it?
Pancreatic calcifications develop when chronic inflammation or damage leads to calcium deposits within the pancreatic ducts or tissue. They are a hallmark of chronic pancreatitis, where repeated episodes of inflammation cause scarring, ductal obstruction, and eventual mineralization. Less commonly, calcifications may appear with metabolic disorders, congenital abnormalities, or certain tumors such as pancreatic neuroendocrine tumors.
Imaging, particularly CT, is essential for identifying calcifications and assessing their distribution. The pattern—whether within the pancreatic ducts, scattered throughout the pancreas, or associated with a mass—helps radiologists determine the underlying cause and guide further evaluation.
Important to Know
Pancreatic calcifications often reflect long-term pancreatic disease and may be associated with digestive problems or diabetes if enough tissue is damaged. Chronic pancreatitis can lead to pain, impaired digestion due to enzyme deficiency, or complications such as strictures, pseudocysts, or blockages of the ducts.
Red flag symptoms include severe or persistent upper abdominal pain, vomiting, jaundice, fever, or unexplained weight loss. These may indicate active inflammation, infection, or complications requiring urgent evaluation. Follow-up imaging may be needed to assess disease progression or monitor associated findings.